Vitamin B12 10ml

Description

Vitamin B12 Overview

Vitamin B12 is supplied here as cyanocobalamin, a cobalt-containing corrinoid compound and the most chemically stable form of the vitamin. Unlike the lyophilized peptides in this catalog it ships as a sterile solution at 1000 mcg per millilitre in a sealed multi-dose vial, ready for use as a reference standard or as a supporting reagent alongside other research compounds.

Cobalamin Cofactor Chemistry

The molecule is built around a corrin ring with a central cobalt atom, which can carry a cyano, methyl, adenosyl or hydroxo group at its upper axial position. Cyanocobalamin is a synthetic form that converts in biological systems to the two active cofactors, methylcobalamin and adenosylcobalamin.

Two Enzymatic Roles

In mammalian biochemistry, cobalamin serves exactly two enzymes. Methylcobalamin is the cofactor for methionine synthase, which remethylates homocysteine to methionine and links B12 status to folate metabolism and one-carbon transfer. Adenosylcobalamin is the cofactor for methylmalonyl-CoA mutase in the mitochondrion, which converts methylmalonyl-CoA to succinyl-CoA. Accumulation of methylmalonic acid and homocysteine are the two standard laboratory markers of functional deficiency.

Handling and Light Sensitivity

Cobalamin solutions are photosensitive and degrade on prolonged exposure to light, which is why the solution carries its characteristic deep red colour and should be kept in its carton until use. Store at controlled room temperature.

Specifications

• CAS Number: 68-19-9
• Molecular Formula: C63H88CoN14O14P
• Molar Mass: 1355.38 g/mol
• Class: Corrinoid (cobalt coordination compound)
• Concentration: 1000 mcg per mL
• Storage: Controlled room temperature. Protect from light.
• Form: Sterile solution in a sealed multi-dose glass vial.
• Purity: Minimum 98%
• Quantity: 10ml per vial
• Color: Deep red

Important Note: This product is intended solely for in vitro laboratory research by licensed professionals. It is not approved by the FDA for human or animal use and should not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.

References:

1. Green R. et al. – Vitamin B12 deficiency – Nature Reviews Disease Primers
2. Banerjee R. & Ragsdale S.W. – The many faces of vitamin B12 – Annual Review of Biochemistry
3. Stabler S.P. – Vitamin B12 deficiency – New England Journal of Medicine
4. Quadros E.V. – Advances in the understanding of cobalamin assimilation and metabolism – British Journal of Haematology

You may also like

BAC Water 10ml$18.00Energy Stack$569.00 Original price was: $569.00.$399.00Current price is: $399.00.Starter Sample Stack$910.00 Original price was: $910.00.$499.00Current price is: $499.00.