Description
Semax Peptide Overview
Semax is a synthetic heptapeptide analog of the ACTH(4-10) fragment of adrenocorticotropic hormone, modified for stability. Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, it is one of the most studied nootropic and neuroprotective peptides in research.
BDNF and NGF Expression
Semax is studied for rapidly increasing the expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) and their receptors, a pathway central to neuroplasticity and neuronal survival research.
Cognitive and Nootropic Research
As an ACTH(4-10) analog stripped of hormonal activity, Semax is investigated for effects on attention, memory and learning in cognitive research models.
Neuroprotection
Semax is studied for neuroprotective signaling under conditions of oxidative and ischemic stress, and for modulation of the dopaminergic and serotonergic systems.
Melanocortin System Activity
Deriving from ACTH, Semax is studied for interactions with the melanocortin system that contribute to its neurotrophic and neuroprotective research profile.
Specifications
- CAS Number: 80714-61-0
- Molecular Formula: C37H51N9O10S
- Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
- Molar Mass: 813.92 g/mol
- Class: Synthetic heptapeptide (ACTH(4-10) analog)
- Storage: Refrigerate after reconstitution.
- Form: Lyophilized powder in a sterile glass vial.
- Purity: Minimum 99%
- Quantity: 5mg per vial
- Color: White
Important Note: This product is intended solely for in vitro laboratory research by licensed professionals. It is not approved by the FDA for human or animal use and should not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.
References:
- Kaplan A.Ya. et al. – Synthetic ACTH analogue Semax as a nootropic – Neuroscience and Behavioral Physiology
- Dolotov O.V. et al. – Semax activates the BDNF/TrkB system – Journal of Neurochemistry
- Shadrina M. et al. – Semax and neuroprotection – Frontiers in Pharmacology
- ACTH(4-10) analogs and cognition – Peptides

Reviews
There are no reviews yet.