Description
NAD+ Overview
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell and one of the most important molecules in cellular metabolism. It is a central subject in energy-metabolism and longevity research due to its declining levels with age.
Central Role in Energy Metabolism
NAD+ acts as an electron carrier in the redox reactions of glycolysis, the TCA cycle and oxidative phosphorylation, making it essential to the production of cellular ATP — a core focus of bioenergetics research.
Sirtuin and PARP Activity
NAD+ is a required substrate for sirtuins and PARP enzymes, which regulate DNA repair, gene expression and stress responses. Research studies how NAD+ availability governs these longevity-associated pathways.
Aging and NAD+ Decline
Cellular NAD+ levels decline with age, and research investigates how restoring NAD+ influences mitochondrial function, metabolic health and age-related cellular changes.
Specifications
- CAS Number: 53-84-9
- Molecular Formula: C21H27N7O14P2
- Molar Mass: 663.43 g/mol
- Class: Dinucleotide coenzyme
- Storage: Refrigerate after reconstitution.
- Form: Lyophilized powder in a sterile glass vial.
- Purity: Minimum 99%
- Quantity: 500mg per vial
- Color: White
Important Note: This product is intended solely for in vitro laboratory research by licensed professionals. It is not approved by the FDA for human or animal use and should not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.
References:
- Verdin E. – NAD+ in aging, metabolism and neurodegeneration – Science
- Rajman L. et al. – Therapeutic potential of NAD-boosting molecules – Cell Metabolism
- Covarrubias A.J. et al. – NAD+ metabolism and its roles in cellular processes – Nature Reviews Molecular Cell Biology

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