NAD+ (500mg / 1000mg)

Description

NAD+ Overview

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell and one of the most important molecules in cellular metabolism. It is a central subject in energy-metabolism and longevity research due to its declining levels with age.

Central Role in Energy Metabolism

NAD+ acts as an electron carrier in the redox reactions of glycolysis, the TCA cycle and oxidative phosphorylation, making it essential to the production of cellular ATP — a core focus of bioenergetics research.

Sirtuin and PARP Activity

NAD+ is a required substrate for sirtuins and PARP enzymes, which regulate DNA repair, gene expression and stress responses. Research studies how NAD+ availability governs these longevity-associated pathways.

Aging and NAD+ Decline

Cellular NAD+ levels decline with age, and research investigates how restoring NAD+ influences mitochondrial function, metabolic health and age-related cellular changes.

Specifications

• CAS Number: 53-84-9
• Molecular Formula: C21H27N7O14P2
• Molar Mass: 663.43 g/mol
• Class: Dinucleotide coenzyme
• Storage: Refrigerate after reconstitution.
• Form: Lyophilized powder in a sterile glass vial.
• Purity: Minimum 99%
• Quantity: 500mg / 1000mg per vial (select size)
• Color: White

Important Note: This product is intended solely for in vitro laboratory research by licensed professionals. It is not approved by the FDA for human or animal use and should not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.

References:

1. Verdin E. – NAD+ in aging, metabolism and neurodegeneration – Science
2. Rajman L. et al. – Therapeutic potential of NAD-boosting molecules – Cell Metabolism
3. Covarrubias A.J. et al. – NAD+ metabolism and its roles in cellular processes – Nature Reviews Molecular Cell Biology

A note on NAD+ purity. NAD+ is inherently unstable and is typically present alongside its own degradation products — ADP-ribose, nicotinamide, NMN and AMP. This is expected for the compound rather than a sign of contamination, which is why NAD+ assays below the purity figures seen for our stable peptides. The lab notes this directly on the certificate.

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