Description
Melanotan II Peptide Overview
Melanotan II is a synthetic cyclic analog of alpha-melanocyte-stimulating hormone (α-MSH). It is one of the most studied melanocortin peptides in pigmentation research, valued for its potent, non-selective activity across melanocortin receptors.
Melanogenesis Research
Melanotan II strongly activates the MC1R receptor on melanocytes, the pathway that drives melanogenesis — the synthesis of melanin. This makes it a primary subject of pigmentation and photoprotection research models.
Non-Selective Melanocortin Activity
Unlike more receptor-selective analogs, Melanotan II engages multiple melanocortin receptors (MC1R, MC3R, MC4R, MC5R), which is studied for a broad range of melanocortin-mediated effects.
Research Applications
Beyond pigmentation, Melanotan II’s melanocortin activity is investigated in appetite and behavioral research models due to MC4R engagement.
Specifications
- CAS Number: 121062-08-6
- Molecular Formula: C50H69N15O9
- Molar Mass: 1024.18 g/mol
- Class: Non-selective melanocortin receptor agonist (cyclic heptapeptide, α-MSH analog)
- Storage: Refrigerate after reconstitution.
- Form: Lyophilized powder in a sterile glass vial.
- Purity: Minimum 99%
- Quantity: 10mg per vial
- Color: White
Important Note: This product is intended solely for in vitro laboratory research by licensed professionals. It is not approved by the FDA for human or animal use and should not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.
References:
- Dorr R.T. et al. – Melanotan II and melanogenesis – Life Sciences
- Melanocortin receptor agonists and pigmentation – Peptides
- Central and peripheral melanocortin signaling – Pharmacological Reviews

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