Description
SS-31 (Elamipretide) Peptide Overview
SS-31, also known as elamipretide, is a synthetic mitochondria-targeting tetrapeptide from the Szeto-Schiller family of peptides. It is one of the most studied compounds in mitochondrial-bioenergetics research due to its selective localization to the inner mitochondrial membrane.
Cardiolipin Binding
SS-31 selectively binds cardiolipin, a phospholipid unique to the inner mitochondrial membrane. This interaction is studied for stabilizing the structure of mitochondrial cristae and supporting the efficiency of the electron-transport chain.
Reduces Reactive Oxygen Species
By protecting cardiolipin and improving electron-transport integrity, SS-31 is studied for reducing the production of reactive oxygen species (ROS) and limiting oxidative stress in research models.
Bioenergetics and Cellular Protection
Research on SS-31 focuses on preserving ATP production and protecting cells with high energy demand, making it a key tool in mitochondrial and age-related research.
Specifications
- CAS Number: 736992-21-5
- Molecular Formula: C32H49N9O5
- Sequence: D-Arg-2,6-dimethyl-Tyr-Lys-Phe-NH2
- Molar Mass: 639.79 g/mol
- Class: Mitochondria-targeting tetrapeptide
- Storage: Refrigerate after reconstitution.
- Form: Lyophilized powder in a sterile glass vial.
- Purity: Minimum 99%
- Quantity: 30mg per vial
- Color: White
Important Note: This product is intended solely for in vitro laboratory research by licensed professionals. It is not approved by the FDA for human or animal use and should not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.
References:
- Szeto H.H. – Cardiolipin-targeting peptides and mitochondrial protection – British Journal of Pharmacology
- Birk A.V. et al. – SS-31 and the inner mitochondrial membrane – Journal of the American Society of Nephrology
- Elamipretide and mitochondrial bioenergetics – Circulation Research

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