Description
KPV Peptide Overview
KPV is a naturally occurring tripeptide (lysine-proline-valine) corresponding to the C-terminal fragment of alpha-melanocyte-stimulating hormone (α-MSH). It is studied in research primarily for its anti-inflammatory signaling.
Anti-Inflammatory Signaling
KPV is studied for its ability to enter cells and down-regulate pro-inflammatory pathways, including NF-κB signaling and the production of inflammatory cytokines, in research models.
Gut Inflammation Research
A prominent area of KPV research is the intestinal tract, where it is investigated in models of colitis and mucosal inflammation for its effects on epithelial cells and immune signaling.
Skin and Tissue Research
KPV’s anti-inflammatory activity is also studied in dermal and wound-related research models, where inflammation influences tissue outcomes.
Specifications
- CAS Number: 67727-97-3
- Molecular Formula: C16H30N4O3
- Sequence: Lys-Pro-Val (L-Lysyl-L-Prolyl-L-Valine)
- Molar Mass: 326.44 g/mol
- Class: Anti-inflammatory tripeptide (α-MSH C-terminal fragment)
- Storage: Refrigerate after reconstitution.
- Form: Lyophilized powder in a sterile glass vial.
- Purity: Minimum 99%
- Quantity: 10mg per vial
- Color: White
Important Note: This product is intended solely for in vitro laboratory research by licensed professionals. It is not approved by the FDA for human or animal use and should not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.
References:
- Dalmasso G. et al. – KPV and intestinal inflammation – American Journal of Physiology: GI and Liver Physiology
- Anti-inflammatory activity of the α-MSH tripeptide KPV – Journal of Immunology
- Melanocortin peptides and NF-κB signaling – Peptides

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