Description
TB-500 Peptide Overview
TB-500 is a synthetic peptide based on the naturally occurring protein Thymosin Beta-4 (Tβ4), an actin-binding regulator found throughout the body. In research it is studied for its central role in cell migration, tissue repair, and the regeneration of muscle, tendon and other connective tissues.
Promotes Cell Migration and Repair
TB-500 binds G-actin and regulates the actin cytoskeleton, a process that enables cells to migrate to sites of injury. This mechanism is studied for accelerating the repair of muscle, tendon, ligament and skin in research models.
Stimulates Angiogenesis
Like other repair-associated peptides, TB-500 is studied for promoting the formation of new blood vessels, improving circulation to damaged tissue and supporting the delivery of oxygen and nutrients during recovery.
Reduces Inflammation and Scar Tissue
Research indicates TB-500 can down-regulate inflammatory signaling and influence collagen organization, which is studied for reducing excessive scar formation and improving the quality of repaired tissue.
Supports Flexibility and Recovery
Through its effects on actin and connective tissue, TB-500 is investigated for improving tissue flexibility and shortening recovery timelines in musculoskeletal research models.
Additional Research Interest
TB-500 / Thymosin Beta-4 has also been studied in models of cardiac tissue repair, corneal and dermal wound healing, and hair-follicle research.
Specifications
- CAS Number: 77591-33-4
- Molecular Formula: C212H350N56O78S
- Sequence: based on Thymosin Beta-4 (Tβ4); active region Leu-Lys-Lys-Thr-Glu-Thr-Gln
- Molar Mass: approx. 4963 g/mol
- Class: Peptide (Thymosin Beta-4 derivative)
- Storage: Refrigerate after reconstitution.
- Form: Lyophilized powder in a sterile glass vial.
- Purity: Minimum 99%
- Quantity: 10mg per vial
- Color: White
Important Note: This product is intended solely for in vitro laboratory research by licensed professionals. It is not approved by the FDA for human or animal use and should not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.
References:
- Goldstein A.L., Kleinman H.K. – Advances in the basic and clinical applications of thymosin β4 – Expert Opinion on Biological Therapy
- Thymosin β4: actin sequestration and cell migration – Annals of the New York Academy of Sciences
- Thymosin β4 promotes angiogenesis and wound repair – Journal of Investigative Dermatology
- Bock-Marquette I. et al. – Thymosin β4 and cardiac repair – Nature
- Thymosin β4 in tissue regeneration – Annals of the New York Academy of Sciences

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